Meta-Analysis of Prospective Cohort Studies Evaluating the Association of Saturated Fat with Cardiovascular Disease

This meta-analysis reviewed evidence from observational studies on the link between dietary saturated fat and risk of heart disease and stroke.

The studies included a total of 347,747 participants, who were followed for 5–23 years.

Results: During follow up, about 3% of participants (11,006 people) developed heart disease or stroke.

Saturated fat intake was not linked with an increased risk of cardiovascular disease, heart attacks or strokes, even among those with the highest intake.

Conclusion: This study did not find any association between saturated fat intake and cardiovascular disease.

Siri-Tarino PW, et al. Meta-analysis of prospective cohort studies evaluating the association of saturated fat with cardiovascular disease. American Journal of Clinical Nutrition, 2010.

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