Intake of Saturated and Trans Unsaturated Fatty Acids and Risk of All Cause Mortality, Cardiovascular Disease, and Type 2 Diabetes

This systematic review and meta-analysis reviewed observational studies on the association of saturated fat and heart disease, stroke, type 2 diabetes and death from cardiovascular disease.

The data included 73 studies, with 90,500–339,000 participants for each endpoint.

Results: Saturated fat intake was not linked with heart disease, stroke, type 2 diabetes or dying of any cause.

Conclusion: People who consumed more saturated fat were not more likely to experience heart disease, stroke, type 2 diabetes or death from any cause, compared to those who ate less saturated fat.

However, the results from the individual studies were very diverse, so it is hard to draw an exact conclusion from them.

The researchers rated the certainty of the association as “low,” emphasizing the need for more high-quality studies on the subject.

De Souza RJ, et al. Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies. BMJ, 2015.

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