‘Body Clock’ Dysregulation Underlies Obesity

A team of Texas A&M University System scientists have investigated how “body clock dysregulation” might affect obesity-related metabolic disorders.

Medical Press: Study shows how ‘body clock’ dysregulation underlies obesity, more

Earnest said results showed that during obesity, that is when mice were fed a high-fat diet, the rhythmicity of circadian clocks in immune cells of fat tissue is dysregulated by a prolonged rhythmic period. This is, in turn, is linked to increased accumulation of immune cells in fat tissue and decreased whole-body insulin sensitivity.

Earnest and Wu said the study will help those involved in human health and nutrition better understand the underlying mechanisms related to obesity and diabetes.

Medical Press: Study shows how ‘body clock’ dysregulation underlies obesity, more

 

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